A weekly round-up of some of the most interesting One Medicine-related happenings we've found this week:
Researchers work to understand how multi-pathogen epidemics evolve - we're all connected
“Disease biology and epidemiology have historically focused on one-on-one interactions: one pathogen, one host,” said Rudolf, a professor of biosciences at Rice. “However, scientists increasingly recognize that diseases don’t exist in a vacuum. In reality, a diverse community of parasites and pathogens are out there, and they interact with each other. This study emphasizes a more holistic, almost community type of approach to studying infectious diseases.” (Bioengineer.org)
Approved drug screen throws up compounds that prevent bacterial acquisition of DNA-borne antibiotic resistance traits from surroundings
"[Researchers] found that with 46 of the tested drugs, the bacteria failed to become competent but continued to grow. These included drugs in two categories: those which prevented the cell from maintaining the proper balance of ions inside and outside the cell, and those which were used to treat psychotic conditions." (News-medical.net)
New paper highlights how initially minor ecosystem changes can eventually lead to huge shifts- applies to human events too
“Our model shows the evolutionary mechanism by which a sudden change -- like an ecosystem or financial collapse -- may be the result of a small environmental change in the distant past." (Science Daily)
The AKC Canine Health Foundation Awards Over $2.1 Million in New Canine Health Research Grants. 36 new research projects funded to tackle canine cancers including lymphoma, osteosarcoma, bladder cancer, soft tissue sarcoma, and hemangiosarcoma. Also neurological disorders including meningoencephalomyelitis of unknown origin (which resembles human multiple sclerosis) and canine degenerative myelopathy (which resembles human ALS).
Changing Our Habits Will Improve Equine Welfare Say Experts At National Equine Forum. Outline of forum discussion on how human behaviour change can help improve equine health, including how changing behaviours could tackle the problematic emergence of anti-helminthics resistance, after "50 years of indiscriminate use".
Blog post of the week:
The APHA science blog: Why wildlife health issues are not just a biodiversity concern.
How the UK strives to stay free of parasitic tapeworm Echinococcus multilocularis, monitoring wild boar populations as a wildlife reservoir in the UK, and tracking ongoing incidences of antimicrobial resistant infections in seals on the north-east UK coast.
(5 min read and some great map figures)
Nextstrain.org is an 'open-source project to harness the scientific and public health potential of pathogen genome data.' Check out the site's beautiful data-driven real-time graphics showing the genomic evolution of HCoV-19 and other pathogens over time and geography.